scientists
Seminar
Using Lessons from Development to Regenerate Retinal Neurons
2022
Mammals are unable to regenerate lost neurons. However, strategies are rapidly advancing to stimulate endogenous regeneration by reprogramming glia into neurogenic progenitors. In this work, we outline a strategy to regenerate retinal ganglion cells in the adult mouse retina in vivo by overexpressing developmental transcription factors in Müller glia.